Keywords: Genzyme, Renvela, PPB, Kidney disease, Research
Genzyme’s woes continue as it drops investigational APB follow-up for Renvela, after poor trial results
Article | 19 November 2009
US biotechnology major Genzyme has reported results of a Phase II/III study of its advanced phosphate binder (APB), a stronger version of its already-marketed kidney disease drug Renvela (sevelamer carbonate), which met its primary endpoint, which was to show that the APB lowered phosphate levels effectively compared to placebo in patients with chronic kidney disease. However, the APB did not show a significant improvement in phosphate lowering compared to Renvela.
Based on these results, the company is not planning to pursue further clinical development of the new APB. Enjoying this article? To continue reading you need to login, take a FREE trial or subscribe.
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