$60 million AstraZeneca milestone payment for Eccogene

24 October 2024

Sino-America clinical-stage biotech Eccogene announced that it will receive a $60 million payment from AstraZeneca (LSE: AZN), which is being triggered by successfully achieving milestones related to the development of ECC5004/AZD5004 including the first patient dosed in the Phase IIb program.

VISTA (NCT06579092) and SOLSTICE (NCT06579105) are two global Phase IIb multicenter trials assessing the efficacy and safety of ECC5004/AZD5004, administered orally, once daily, to participants who are obese or overweight with at least one weight-related comorbidity and type 2 diabetes, respectively.

AstraZeneca licensed the global rights to ECC5004/AZD5004 from Eccogene in November 2023, for which the company received an upfront payment of $185 million is eligible for up to $1.825 billion in future milestones, as well as royalty payments. Eccogene retains co-development and co-commercialization rights to ECC5004/AZD5004 in China.

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