German drug major Boehringer Ingelheim will present new data on one of its lead oncology compounds, BIBW 2992, at the annual meeting of the American Society of Clinical Oncology due to be held at the end of May.
Interim Phase II data from the LUX-Lung 2 study suggest BIBW 2992 has anti-tumour activity in advanced second-line non-small cell lung cancer patients who have epidermal growth factor receptor mutations.
64% of patients taking BIBW 2992 in the second-line setting experienced a partial response (75% among patients with deletion 19 and 66% in patients with L858R mutations). 31% experienced stable disease. Meanwhile, median progression-free survival was 10.2 months.
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