Abbott and Enanta to begin Ph I HCV trial
The USA's Abbott Laboratories and Enanta Pharmaceuticals have begun a first-in-human study evaluating ABT-450, an oral protease inhibitor for the treatment of chronic hepatitis C virus. The Phase I, double-blind, placebo-controlled study is a single, ascending oral dose trial in healthy volunteers.
"Hepatitis C is a serious global health concern, with 170 million people currently infected by six different HCV genotypes," said John Leonard, senior vice president of global R&D for Abbott.
"ABT-450 demonstrated favorable potency in vitro across various HCV genotypes and highly-resistant strains," added Enanata chief executive Jay Luly.
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