Belgian biopharmaceutical firm Ablynx, a pioneer in the discovery and development of Nanobodies, a novel class of antibody-derived therapeutic proteins, has expanded its musculoskeletal research portfolio by transferring in-house full ownership of a bone disorder R&D program initiated under its collaboration with Procter & Gamble Pharmaceuticals, started in 2004.
This is Ablynx' second musculoskeletal project and it complements ALX-0141, the company's Nanobody against receptor activator for nuclear factor kappa B ligand (RANKL) which is in preclinical development.
Together, the two programs target different mechanisms to treat bone disorders such as osteoporosis. Ablynx plans to accelerate this second agent towards preclinical development once the best lead candidate Nanobody has been selected.
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