Addex' improved GERD drug greater "commerical potential"
Switzerland's Addex Pharmaceuticals has released clinical data showing that the modified-release formulation of ADX10059 has improved commercial potential.
Tolerability was dramatically improved, while a statistically-significant reduction in gastroesophageal reflux was achieved for the second time in clinical trials of this product. The firm says novel formulation is appropriate for longer term twice-daily dosing in Phase IIb gastroesophageal reflux disease and migraine prophylaxis studies scheduled to start in the fourth quarter. ADX10059 is a first-in-class negative allosteric modulator of metabotropic glutamate receptor 5.
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