The USA's Adventrx Pharmaceuticals has granted Shin Poong Pharmaceutical exclusive rights in South Korea to make, use and sell ANX-514 (docetaxel emulsion), one of its two lead product candidates. Under the terms of the deal, Adventrx will receive an upfront cash payment of $300,000 and up to about $2.0 million in regulatory and commercial milestones and royalties on net sales of licensed products. Shin Poong is responsible for all development and commercial activities related to ANX-514 in South Korea. The agent is a reformulation of Sanofi-Aventis' blockbuster chemotherapeutic agent, Taxotere, which is used to treat breast, non-small cell lung, prostate, head and neck and gastric cancers. In 2007, Taxotere's aggregate worldwide market was in excess of $3.0 billion.
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