US firm Affymetrix and Medical Prognosis Institute, a leading cancer diagnostic development company based in Denmark, have signed an agreement under which MPI gains non-exclusive access to the former's microarray technology to develop and commercialize drug-sensitivity prediction and prognostic products for patients with cancer.
Of 179 new anti-cancer drugs tested in Phase I trials between 1976 and 1993, only 28% were considered effective in Phase III. MPI believes the lack of effect is highly correlated to the response rate, and is now pursuing the opportunity to identify responders; for example, for failed Phase III cancer drugs. Based on Affymetrix microarray technology, MPI aims to market its own proprietary products targeted at individual cancer prognosis and prediction of anti-cancer treatment response.
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