Norwegian cancer therapeutics company Algeta has started patient recruitment in a pivotal Phase III clinical study of its monthly bolus injection Alpharadin (radium-223; Marketletters passim) in advanced, hormone-refractory prostate cancer that has metastasized to the skeleton.
The ALSYMPCA study is a double-blind, randomized, controlled trial that enrols symptomatic HRPC patients who will be randomized to receive Alpharadin plus best standard of care or placebo plus best standard of care. Approximately 750 patients are expected to be enrolled at more than 125 medical centers in Europe, Asia, South America and Canada.
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