Alseres' Rho blocker shows strong early data
The USA's Alseres Pharmaceuticals says that encouraging data from preclinical studies of its regenerative therapy candidate, ALSE-100, were presented at the Australian and New Zealand Bone and Mineral Society annual conference, held in Melbourne, Australia.
The study investigated the effects of ALSE-100 on osteoblast and osteoclast cells in culture, as well as in an organ culture system. ALSE-100 stimulated differentiation and mineralization to form bone nodules in culture and also inhibited bone resorption, osteoclast development and activity. These effects indicate that ALSE-100 could be useful in promoting bone healing.
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