The results of two new meta-analyses suggest that Sanofi-Aventis' obesity treatment Acomplia (rimonabant) may increase the risk of developing anxiety and depression. The findings, published separately in The Lancet and on the British Medical Journal's web site, follow both a Food and Drug Administration non-approval decision and, in Europe, where Acomplia is licensed, a recommendation that patients with depressive conditions do not use the drug (Marketletters June 18 and July 30).
More withdrawals due to depression
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Chairman, Sanofi Aventis UK
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