The College of Pharmacy at Oregon State University, USA, has published research indicating that drugs which are supposed to be prescribed for serious mental illnesses are being given at low doses to patients for conditions where the agents' benefit have not been established. The study, funded by the National Institutes of Health, was published by the Journal of Clinical Psychology and carried out in partnership with Columbia University and the Oregon Health and Science University.
Among the findings of the research team, drugs costing $20-$25 per day were used to treat depression, anxiety, post-traumatic stress disorder or even insomnia, despite the products being designed for use in cases of schizophrenia and bipolar disorder. Daniel Hartung, one of the study's authors, said: "some drug companies have been accused of encouraging and expanding the off-label use of drugs and that may be where part of this misinformation is coming from." He added that, "regardless of what's causing this, it's a serious concern, both for ensuring resources are used judiciously and protecting health care quality."
In Oregon, the state Medicaid program spent $2.5 million for the chronic "subtherapeutic" use of one antipsychotic agent in adult patients alone, the researchers claim. Nearly 30% of all out-patient fee-for-service drug spending in 2006 was accounted for by strong antipsychotics.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2025 | Headless Content Management with Blaze