ICER issues Evidence Report on COVID-19 treatments

28 March 2022

The USA-based Institute for Clinical and Economic Review (ICER) today posted its revised Evidence Report assessing the comparative clinical effectiveness and value of the following treatments for COVID-19:

Xevudy (sotrovimab), from GlaxoSmithKline (LSE: GSK) and Vir Biotechnology (Nasdaq: VIR);
Lagevrio (molnupiravir, from Merck & Co (NYSE: MRK);
Paxlovid (PF-07321332/ritonavir), from Pfizer (NYSE: MRK); and
fluvoxamine (Investigator initiated).

“The evidence on outpatient treatments for COVID-19 must be viewed as highly sensitive to the evolving landscape of COVID-19 variants and vaccination status in the US,” said ICER president Dr Steven Pearson, adding: “What we have today, however, does suggest that the drugs of interest are all – to different degrees – able to reduce hospitalizations among patients with mild-to moderate COVID-19 who are at high risk of progression to severe disease.

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