Anglo-Swedish drug major AstraZeneca says its Seroquel (quetiapine fumarate) significantly increased the time to recurrence of any mood event in patients with bipolar I disorder, according to long-term clinical trial data.
Results, published in the Journal of Affective Disorders from a large-scale, international, randomized, double-blind study, known as Study 126, investigated the time to recurrence of mood event in 1,461 patients with bipolar I disorder initially stabilized for at least 12 weeks with open label Seroquel (400-800mg/day) plus lithium or divalproex.
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