US drug major Bristol-Myers Squibb has agreed to develop a Phase Ib-stage hepatitis C drug made by US firm ZymoGenetics in a deal worth up to $1.12 billion.
Under the terms of the accord, B-MS will make an upfront cash payment of $85.0 million for rights to the novel type 3 interferon, PEG-Interferon lambda, and pay an additional license fee of $20.0 million in 2009. ZymoGenetics' share price leapt 56% to $4.87 in pre-market trading.
ZymoGenetics could receive further payments of up to $430.0 million based on pre-defined milestones for PEG-Interferon lambda in hepatitis C, up to $287.0 million in development and regulatory achievements for other potential indications, and up to $285.0 million based on pre-defined sales-based milestones.
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