BioFocus DPI launches five new compound libraries

Five novel hit-finding compound libraries targeting the ion channel gene family have been released by BioFocus DPI. Created using advanced modeling tools, these new libraries are specifically aimed at voltage-dependent and ligand-gated channels, two of the most important and commonly chosen classes of ion channels for drug discovery, the company claims.

The three new SoftFocus Ion Channel (SFI) libraries target voltage-dependent channels, primarily focusing on sodium and calcium channels to complement BioFocus DPI's earlier libraries focused on potassium channels. These libraries were designed using BioFocus DPI's proprietary chemogenomic tool Helical Domain Recognition Analysis.