Zydus launches world’s first biosimilar to Opdivo

22 January 2026

India’s Zydus Lifesciences (BOM: 532321), an innovation-led life-sciences company with an international presence, has launched the world’s first biosimilar of nivolumab in India under the brand name Tishtha, reinforcing the company’s growing capability in advanced biologics and immuno-oncology.

Tishtha will be available in 100mg and 40mg dosages priced at 28,950 rupees (~$316) and 13,950 rupees respectively. The prices are approximately a quarter of the reference drug, Bristol Myers Squibb’s (NYSE: BMY) Opdivo. Global sales of Opdivo in the third quarter of 2025 were $2.5 billion.

This will improve affordability and reduce the overall treatment burden for patients. The two strength portfolio enables oncologists to optimize dosing and minimize wastage – a key driver of treatment economics in immunotherapy, the company noted.

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