Adding Lynparza and Imfinzi to chemo and bevacizumab aids PFS, trial shows
Positive high-level results from a planned interim analysis of the DUO-O Phase III trial have been presented by Anglo-Swedish drugmaker AstraZeneca (LSE: AZN), which was subsequently trading 2% higher by lunchtime Wednesday.
The results show that adding AstraZeneca’s drugs Lynparza (olaparib) and Imfinzi (durvalumab) to chemotherapy and bevacizumab led to a statistically-significant and clinically-meaningful improvement in progression-free survival (PFS) in newly-diagnosed patients with advanced high-grade epithelial ovarian cancer without tumor BRCA mutations.
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