Apogee progressing zumilokibart on positive Phase II data

24 March 2026

Shares of US clinical-stage biotech Apogee Therapeutics (Nasdaq: APGE) closed up 20% at $79.24 yesterday, when it released positive 52-week maintenance data from Part A of the Phase II APEX clinical trial of zumilokibart (APG777), a potential best-in-class anti-interleukin (IL)-13 antibody, in patients with moderate-to-severe atopic dermatitis (AD).

The results demonstrated durable maintenance of response with both 3- and 6- month maintenance dosing regimens. Deepening of response for the full population across all lesional and itch endpoints was also observed, supporting zumilokibart’s potentially differentiated profile, including significantly less frequent dosing than current standard of care.

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