Arrowhead jumps on news of $2B deal with Novartis

2 September 2025

US biotech Arrowhead Pharmaceuticals (Nasdaq: ARWR) today announced a global licensing and collaboration agreement with Swiss pharma giant Novartis (NOVN: VX) for ARO-SNCA, The US firm’s shares rose 10.5% to $24.36 by mid-morning.

The accord is for Arrowhead’s pre-clinical stage siRNA therapy against alpha-synuclein for the treatment of synucleinopathies, such as Parkinson’s disease, and for other additional collaboration targets that will utilize Arrowhead’s proprietary Targeted RNAi Molecule (TRiM) platform.

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