Astellas' Phase III trial of gilteritinib disappoints

9 March 2023

The US subsidiary of Japanese drug major Astellas Pharma (TYO: 4503) today announced disappointing top-line results from the Phase III MORPHO clinical trial evaluating gilteritinib as a maintenance therapy following allogeneic hematopoietic stem cell transplantation (HSCT) for patients with FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) mutated acute myeloid leukemia (AML).

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