
New York-based Boulevard Bio today announced its emergence from stealth with $65 million from founding investor Deerfield Management and early Phase I healthy volunteer data for lead candidate BLVD101, a dual BAFF/APRIL-targeting bispecific antibody, supporting a 12-week (quarterly) dosing interval in IgA nephropathy (IgAN).
Founded by pioneers in B cell biology and incubated by Deerfield Management within Deerfield Discovery and Development (3DC), the firm's internal therapeutics research and development engine, Boulevard's approach is grounded in a deep understanding of B cell disease biology, the identification of key mechanisms and targets that drive pathology, and the ability to engineer multi-specific antibodies to address those drivers. The company aims to optimize each of the three candidates in its pipeline to improve the quality of life a chronic illness often erodes.
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