CMC Biologics to manufacture TriTAC molecules for Harpoon
Biopharmaceutical contract development and manufacturing organization (CDMO) CMC Biologics, part of Asahi Glass Company (TYO: 5201), today revealed it has entered into an agreement for the development and manufacturing of HPN424, HPN536, and HPN217, representing three TriTAC molecules for the treatment of various human cancers from California biotech Harpoon Therapeutics.
Harpoon Therapeutics’ TriTAC molecules are half-life extended and designed to simultaneously bind to cancer cells and T-cells, triggering those T-cells to attack the targeted cancer cells. Harpoon’s first clinical candidate, HPN424, a prostate-specific membrane antigen (PSMA)-targeting TriTAC, is in development for the treatment of metastatic prostate cancer and expected to enter Phase I clinical trials in 2018.
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