Denosumab reduces burden of giant-cell tumor of the bone
Treatment with denosumab, a drug from Amgen (Nasdaq: AMGN), the world’s largest biotech firm which markets the compound as Xgeva and Prolia, targeted against a protein that helps promote bone destruction, decreased the number of tumor giant cells in patients with giant-cell tumor of the bone, and increased new bone formation, according to the results of a Phase II study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.
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