Domvanalimab failure bad news for Arcus and TIGIT class
US biopharma Arcus Biosciences (NYSE: RCUS) has announced the discontinuation of the Phase III STAR-221 study, being conducted in partnership with Gilead Sciences (Nasdaq: GILD), due to futility.
The Californian company, which is focused on developing differentiated molecules and combination therapies for patients with cancer, inflammatory and autoimmune diseases, closed Friday’s trading 14% lower following the announcement.
Arcus’ decision is based on the recommendation from the Independent Data Monitoring Committee (IDMC) following its review of data from an event-driven, pre-specified interim analysis of overall survival (OS).
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