Enanta ends internal work with NASH FXR agonists

5 October 2021

US biotech Enanta Pharmaceuticals (Nasdaq: ENTA) has delivered an update on its two clinical stage farnesoid X receptor (FXR) agonists, EDP-305 and EDP-297, in non-alcoholic steatohepatitis (NASH).

A pre-planned interim analysis of a subset of patients through week 12 in the Phase IIb ARGON-2 trial of EDP-305 as a monotherapy and data from its Phase I clinical study of EDP-297 provided meaningful information on dose selection and characterization for these compounds.

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