
Engage Biologics, a California-based pre-clinical biotech pioneering non-viral DNA delivery, has revealed that it has been acquired by US pharma major Eli Lilly (NYSE: LLY).
Engage is developing the Tethosome platform, a novel non-viral DNA delivery system designed to overcome key limitations in DNA delivery, including potency, tolerability, and redosability. The platform combines engineered DNA payloads with lipid nanoparticle delivery and an mRNA-encoded proprietary Tethosome technology designed to enhance localization and increase expression. Engage’s DNA payloads are further engineered to improve tolerability while retaining key advantages of DNA-based therapies, including durability and programmability.
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