Erasca partners with Merck on best-in-class pan-RAS molecular glue

12 May 2026

San Diego, USA-based precision oncology company Erasca (Nasdaq: ERAS), which is developing, and commercializing therapies for patients with RAS/MAPK pathway-driven cancers, yesterday announced a clinical trial collaboration and supply agreement (CTCSA) with Merck & Co (NYSE: MRK), known as MSD outside of the USA and Canada.

This agreement supports a clinical proof-of-concept study, AURORAS-1, evaluating the pan-RAS molecular glue ERAS-0015 in combination with Merck’s mega blockbuster drug Keytruda pembrolizumab), for the treatment of patients with RAS-mutant (RASm) solid tumors. Erasca, whose shares closed up 3.2% at $10.44 on the news, is sponsoring the study, and Merck is supplying pembrolizumab at no cost.

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