Further validation for recently-approved Epkinly combination
Danish biotech Genmab (Nasdaq: GMAB) has announced primary data from the pivotal Phase III EPCORE FL-1 study of fixed duration Epkinly (epcoritamab-bysp) alongside rituximab and lenalidomide (Epkinly + R2) in adults with relapsed or refractory (R/R) follicular lymphoma (FL).
The study showed that treatment with Epkinly + R2 reduced the risk of disease progression or death by 79% compared to standard of care R2. The overall response rate (ORR) in patients treated with Epkinly + R2 was 95% compared to 79% in patients treated with R2 .
These results were presented during an oral presentation at the 67th Annual Meeting and Exposition of the American Society of Hematology (ASH) in Orlando, Florida.
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