Genentech's T-DM1 significantly improved survival for metastatic breast cancer patients

29 August 2012

Swiss drug major Roche (ROG: SIX) US subsidiary Genentech has announced updated results from the Phase III EMILIA study, which showed that trastuzumab emtansine (T-DM1) significantly extended the lives (improved overall survival) of people with HER2-positive metastatic breast cancer (mBC) compared to the combination of lapatinib and Xeloda (capecitabine).

The EMILIA study, in people with HER2-positive mBC who had previously received Herceptin (trastuzumab) and taxane chemotherapy, has now met both co-primary efficacy endpoints of significant improvements in overall survival and progression-free survival (PFS), the company said. These data will be presented at an upcoming medical meeting.

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