Gotistobart nearly doubles survival in pretreated squamous lung cancer

14 September 2026

German biotech company BioNTech (Nasdaq: BNTX) and its US partner OncoC4 have put a firm number on a survival benefit they had been describing in general terms for more than a year, reporting mature overall survival (OS) data from the first stage of their Phase III lung cancer trial.

Patients with metastatic squamous non-small cell lung cancer (NSCLC) treated with gotistobart lived a median of 18.5 months, against 10.0 months for those given the chemotherapy docetaxel. The figures come from the non-pivotal stage 1 of the PRESERVE-003 trial and were presented at the 2026 World Conference on Lung Cancer.

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