InflaRx claims 'signals of efficacy' from analyses of terminated vilobelimab trial

30 December 2025

German drug developer InflaRx (Nasdaq: IFRX), which is developing anti-inflammatory therapeutics by targeting the complement system, has outlined multiple data analyses of the Phase III study for vilobelimab in pyoderma gangrenosum (PG).

The trial was terminated earlier this year after an Independent Data Monitoring Committee (IDMC) recommended the trial be stopped early due to futility, causing a 55% drop in the company’s share price.

These newly-presented analyses suggest a positive trend in favor of vilobelimab, with signals indicating a potentially consistent treatment effect.

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