Ipsen to acquire Kartos Therapeutics

29 June 2026

French drugmaker Ipsen (Euronext: IPN) today announced it has entered into a definitive merger agreement to acquire US cancer focused biotech Kartos Therapeutics.

The acquisition adds navtemadlin, an investigational MDM2 inhibitor designed to restore the natural tumor-suppressing function of p53, a critical tumor-suppressor in myelofibrosis. Data show strong therapeutic potential of navtemadlin for intermediate and high-risk TP53 wild-type (wt) myelofibrosis as an add-on treatment for patients with a suboptimal response to standard of care ruxolitinib.

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