J&J strengthens case for earlier Tecvayli use in myeloma
Johnson & Johnson (NYSE:JNJ) has announced positive top-line results from the investigational Phase III MajesTEC-9 study of Tecvayli (teclistamab-cqyv) monotherapy, showing a 71% reduction in the risk of disease progression or death and a 40% drop in the risk of death in a patient population that was predominantly refractory to anti-CD38 therapy and lenalidomide.
Tecvayli was first approved in 2022 in the USA for use in fifth-line patients, and in the European Union in the fourth-line setting.
A significant improvement in PFS and OS as a monotherapy in patients with refractory multiple myeloma
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