Jaw dropping shares leap for Capricor on positive trial for deramiocel in DMD

4 December 2025

US rare diseases focused biotech Capricor Therapeutics (Nasdaq: CAPR) shares closed up 371% at $29.96, having leapt a staggering 500% yesterday, on new research on its Duchenne muscular dystrophy (DMD) candidate.

Capricor announced positive top-line results from its pivotal Phase III HOPE-3 trial evaluating deramiocel, the company’s investigational cell therapy for the treatment of (DMD).

“HOPE-3 delivered strong and definitive evidence that deramiocel can meaningfully improve the course of Duchenne muscular dystrophy, demonstrating statistically significant improvements in both skeletal and cardiac function,” said Dr Linda Marbán, chief executive of Capricor.

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