Lunsumio data shows potential in earlier lymphoma treatment lines
Roche (ROG: SIX) has unveiled a fresh wave of data for Lunsumio (mosunetuzumab), underscoring the Swiss pharma major’s ambition to move its CD20xCD3 bispecific earlier in follicular and large B-cell lymphomas.
The results, presented at the American Society of Hematology (ASH) meeting, sketch out the potential for outpatient, chemotherapy-free regimens built around the drug.
Initial findings from a US extension of the Phase III CELESTIMO trial showed encouraging activity for Lunsumio combined with Bristol Myers Squibb’s (NYSE: BMY) Revlimid (lenalidomide) in second-line or later follicular lymphoma. Among 54 patients, the regimen delivered an 87% complete response rate. The study reported low-grade cytokine release events and manageable infections and neutropenia, with a primary analysis expected next year.
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