MeiraGTx inks ophthalmology collaboration with Lilly
US clinical-stage genetic medicines company MeiraGTx Holdings (Nasdaq: MGTX) saw its shares rise 15% to $9.74 pre-market today, as it announced a broad strategic collaboration in the area of ophthalmology with Eli Lilly (NYSE: LLY).
MeiraGTx will grant Lilly worldwide exclusive rights to its AAV-AIPL1 program for treatment of one of the most severe inherited retinopathies, Leber congenital amaurosis 4 (LCA4) owing to genetic deficiency of aryl-hydrocarbon-interacting protein-like 1 (AIPL1).
Clinical data from 11 children under the age of 4 who were born legally blind as a result of mutations in the AIPL1 gene were unprecedented, with all 11 blind children gaining vision after treatment with AAV-AIPL1. Beyond the effects on vision, treatment with AAV-AIPL1 resulted in life-changing benefits in vital areas of development including communication, behavior, learning, mood, psychological benefits and social integration.
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