Memo moving potravitug to Phase III despite primary endpoint miss

25 July 2025

Privately-held Swiss biotech Memo Therapeutics has announced results from its Phase II trial evaluating potravitug, a highly-potent human BK polyomavirus (BKPyV)-neutralizing monoclonal antibody, for the treatment of BKPyV infection in kidney transplant recipients (KTRs).

Some 95 patients were enrolled in the randomized, double-blind, placebo-controlled SAFE KIDNEY II trial across 22 US sites to evaluate the clinical effectiveness of potravitug in reducing BKPyV infection in blood and kidney tissue.

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