News briefs from Threshold, Merck KGaA and GSK

18 September 2012

US biotech firm Threshold Pharmaceuticals (Nasdaq: THLD) said yesterday that data from a Phase IIb trial of TH-302 in patients with advanced pancreatic cancer will be presented at the European Society for Medical Oncology, Austria, September 28 to October 2, 2012. New finding on overall survival indicate that patients treated with gemcitabine alone had a median overall survival of 6.9 months versus 9.2 months with TH-302 340 mg/m2 + gemcitabine (HR: 0.955, 95% CI: 0.67-1.37, p=0.800) and 8.7 months with TH-302 240 mg/m2 + gemcitabine (HR: 0.960, 95% CI: 0.67-1.38, p=0.827).

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