NICE recommends Genmab’s Tivdak

22 May 2026

The UK’s National Institute for Health and Care Excellence (NICE) has published final draft guidance recommending the use of Tivdak (tisotumab vedotin), an antibody-drug conjugate (ADC), from within its marketing authorization for the monotherapy treatment of adult patients with recurrent or metastatic cervical cancer with disease progression on or after systemic therapy.

This is a U-turn by the health technology assessor, which in March issued draft guidance declining to recommend Tivdak, from Danish biotech Genmab (Nasdaq: GMAB).

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