NodThera rebrands as Rezera, posts positive Phase II data ahead of PAD trial
NodThera, the US biotech developing oral NLRP3 inhibitors, has renamed itself Rezera and announced plans to advance its lead candidate, ruvonoflast, into a Phase III trial in peripheral artery disease (PAD) in the first half of 2027, alongside positive topline data from a Phase II study of the drug.
The company, headquartered in Boston with an R&D base in Cambridge, UK, said the rebrand reflected its shift toward translating NLRP3 science into therapies for cardiovascular and neurological inflammation. It has recently appointed Geoff McDonough as chief executive, Chris Guiffre as chief financial officer and Jyothis George as chief medical officer.
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