Orchard links with Pharming to develop HSC gene therapy for hereditary angioedema

1 July 2021

UK and USA-based clinical-stage gene therapy specialist Orchard Therapeutics (Nasdaq: ORTX) has entered into a strategic collaboration with Dutch firm Pharming Group (Euronext Amsterdam: PHARM) to research, develop, manufacture and commercialize OTL-105, a newly disclosed investigational ex vivo autologous hematopoietic stem cell (HSC) gene therapy for the treatment of hereditary angioedema (HAE), a life-threatening rare disorder that causes recurring swelling attacks in the face, throat, extremities and abdomen.

News of the deal saw Pharming’s shares edge up 2.2% to 0.98 euros in morning trading, but Orchard was flat in pre-market activity.

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