Phase IIb RELIEF trial win with licaminlimab
Swiss ophthalmology specialist Oculis Holding (Nasdaq: OCS) has announced positive top-line results from its Phase IIb RELIEF trial with licaminlimab (OCS-02), a novel anti-TNFα biologic eye drop with an established dual anti-inflammatory and anti-apoptotic mechanism of action in patients with dry eye disease (DED).
The Phase IIb RELIEF trial is a multicenter, randomized, double-masked, vehicle-controlled trial evaluating the efficacy and safety of licaminlimab in subjects with signs of DED ( NCT05896670). The trial also evaluated the efficacy and safety of licaminlimab in a subpopulation of subjects with a TNFR1-related genotype as prespecified in the protocol. The candidate was in-licensed from Swiss pharma giant Novartis (NOVN: VX) in 2019.
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