Positive results with Roche's dry-AMD drug candidate

28 August 2013

Swiss drug major Roche (ROG: SIX) has announced positive results from the Phase II MAHALO study showing that lampalizumab achieved a 20.4% (p<0.1170) reduction rate in the area of geographic atrophy (GA) at 18 months in patients with an advanced form of dry age-related macular degeneration (AMD).

In a specific sub-population of GA patients treated monthly with lampalizumab who were identified using exploratory biomarkers, the GA progression rate was decreased by 44% (p<0.005) at 18 months.

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