Roche advised to stop Ph III onartuzumab METLung study on lack of efficacy
An independent data monitoring committee has recommended that Swiss drug major Roche’s (ROG: SIX) Phase III METLung study be stopped due to a lack of clinically meaningful efficacy. Roche shares dipped 1.9% to 266.30 Swiss francs in early trading.
The study evaluated whether onartuzumab (MetMab) in combination with Tarceva (erlotinib) helped patients with previously-treated, advanced non-small cell lung cancer (NSCLC) whose tumors were identified as MET-positive live longer compared to Tarceva alone. Overall adverse event rates were generally similar between the two groups. Data will be submitted for presentation at a forthcoming medical meeting.
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