There was mixed news coming out of the San Antonio Breast Cancer Symposium (SABCS), which concluded on December 8, with good and bad news from Genzyme and Pfizer (see Pharma Letter December 7), but disappointing findings for others.
Genentech, part of Swiss drug major Roche (ROG: SIX), announced updated survival results from the Phase III CLEOPATRA study, which showed that the combination of Perjeta (pertuzumab), Herceptin (trastuzumab) and docetaxel chemotherapy significantly extended the lives (overall survival) of people with previously untreated HER2-positive metastatic breast cancer (mBC), compared to Herceptin, chemotherapy and placebo.
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