Sirnaomics’ RNAi treatment shows novel mechanism of action for solid tumors

24 January 2024

Sino-American RNAi therapeutics company Sirnaomics (2257: HK) today announced the publication of a research article with NAR Cancer.

The article reveals a novel mechanism of action of lead RNAi cancer drug candidate, STP707, a polypeptide nanoparticle (PNP) formulation comprised of two active siRNA (small interfering RNA) inhibitors targeting TGF-β1 and COX-2 for intravenous treatment of solid tumors. The publication provides support to the company’s ongoing clinical studies and a strong rationale for combination treatment with immune-checkpoint inhibitors.

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