Sunesis tanks as it pulls plug on vecabrutinib program

24 June 2020

Shares of US drug developer Sunesis Pharmaceuticals (Nasdaq: SNSS) plunged 43% to $0.35 by close of trading Tuesday, after it revealed it will not advance its non-covalent BTK inhibitor vecabrutinib into the planned Phase II portion of the Phase Ib/ii trial in adults with relapsed/refractory chronic lymphocytic leukemia (CLL) and other B-cell malignancies.

The decision was made after assessing the totality of the data including the 500mg cohort, the highest dose studied in the trial, and the stock fell a further 5% pre-market today.

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