Value of siponimod to treat SPMS assessed by the ICER

3 May 2019
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An Evidence Report assessing the comparative clinical effectiveness and value of Swiss pharma giant Novartis’ Mayzent (siponimod) for the treatment of secondary progressive multiple sclerosis (SPMS) was released on Thursday by the USA’s Institute for Clinical and Economic Review (ICER).

Siponimod was recently approved by the Food and Drug Administration for the treatment of relapsing forms of multiple sclerosis (MS), including active SPMS. However, cost-effectiveness watchdog ICER’s assessment focuses on the clinical and cost-effectiveness of siponimod for all patients with SPMS (both active and non-active), which was the population studied in the Phase III trial.

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