VarmX agrees $2.1 billion acquisition option in collaboration with CSL

16 September 2025

Dutch biotech VarmX has entered into a strategic collaboration with Australia’s CSL (ASX: CSL), to support the development of its lead asset, VMX-C001, which is a novel treatment to help restore blood coagulation in patients requiring urgent surgery or experiencing severe bleeding while on FXa DOACs.

CSL has also entered into an exclusive option agreement with VarmX shareholders to acquire all issued and outstanding shares of the company.

Under the terms of the strategic collaboration agreement, CSL will fully fund VarmX’s global Phase III EquilibriX-S trial evaluating VMX-C001 in patients taking FXa DOACs who require urgent surgery. CSL will also fully fund and support VarmX in late-stage product development, manufacturing and pre-launch commercial and medical affairs activities.

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